EUROoC-Web-Banner draft 2

24-25 May, 2018

Conference Details

The extremely interdisciplinary field of OoC research is rapidly growing while new and innovative systems are constantly being developed. However, a variety of engineering challenges remain, which the OoC field has to address as a whole to enable a sustainable growth of this breakthrough technology. This meeting will focus on the engineering challenges in the process of designing, fabricating, and implementing microphysiological systems addressing topics such as microfabrication of 3D matrices, integration of miniaturized sensors, microfluidic interfacing, cellular engineering, parallelization and automation, and discussions spanning topics such as developmental biology, drug delivery, 3D cell cultures, organoids, organ-specific models and regulatory aspects.

The first EUROoC meeting calls for scientific contributions addressing the engineering challenges associated with organ-on-chip. The meeting will take place in Stuttgart, Germany, 24-25 May, 2018.

The EUROoC meeting aims to attract leading international researchers for knowledge-sharing and networking with a clear focus on engineering perspectives of organ-on-chip and microphysiological systems. The meeting series would especially like to attract the participation of young and upcoming scientists with the ambition to become the natural meeting place for researchers in the organ-on-chip field in Europe.

The meeting invites oral contributions (à 20 min) as well as poster presentations in the scientific programme. The program will include four plenary speakers and allow ample time for networking in a relaxed and social atmosphere with internationally leading researchers in the dynamic organ-on-chip research community.

Topics for which we are accepting contributions include (but are not limited to):
• Micro- and Nanoengineering
• Microfluidic interfacing
• Actuators for dynamic culture environments
• Integrated sensors
• Cellular engineering
• 3D cell culture environments
• Scaling
• Automation
• User-friendliness

Preliminary Program

May 24, 2018
8:45-9:00 – Welcome and Conference Opening 

9:00-9:50 – Christopher Hughes, University of California – Irvine  A perfused Blood-Brain Barrier on a chip – Keynote

9:50-10:10 – Barbara Bachmann, Vienna University of Technology – Effects of growth factor gradients and indirect flow on vasculature-on-chip

10:10-10:30 – Soheila Zeinali, ARTORG Center, University of Berne – Remodeling of in vitro human vasculature subjected to mechanical stress of the respiration

10:30-11:00 – Coffee Break          

11:00-11:20 – Johanna Chuchuy – Retina-on-a-Chip: Merging Organoid and Organ-on-a-Chip technology for complex multi-layer tissue models

11:20-11:40 – Peter Ertl, Austrian Institute of Technlogy – Microfluidic modelling of Parkinson’s disease with three-dimensional human midbrain organoids

11:40-12:00 – Susanna Piluso, University of Twente – Mimicking synovial inflammation in a bio-inspired synovium-on-a-chip

12:00-12:20 – Julia Rogal, Fraunhofer Institute for Interfacial Engineering and Biotechnology – WAT-on-a-Chip: Microphysiological systems integrating white adipose tissue

12:20-12:40 – Christian Lohasz, ETH Zurich – A versatile microfluidic chip for interconnecting multiple organs

12:40-13:30 – Lunch        

13:30-14:20 – Carsten Werner, Institute for Biofunctional Polymer Materials – Cell instructive biohybrid hydrogels for tissue and disease models – Keynote

14:20-14:40 – Sean S. Searle, National University of Singapore / Uppsala University– Hyaluronic acid based hydrogel droplets: A potential injectable cell culture scaffold

14:40-15:00 – Aisen Vivas, University of Twente – One-step Fabrication of a Monolithic Microfluidic Device with Integrated Extracellular Matrix-derived Membranes for Organ-on-Chip Applications

15:00-15:20 – Wesley Buijsman, University of Twente – Patterning of Collagen Lumens in an Open-Top Organ-on-Chip Device for Co-Culture of Endothelial and Retinal Pigment Epithelial Cells

15:20-16:45 – Poster Session 1 and Coffee Break (15 posters)     

16:45-17:05 – Pauline Zamprogno, ARTORG Center, University of Bern – Development of an air-blood barrier on chip with a biological membrane

17:05-17:25 – Mari Pekkanen-Mattila, BioMediTech, University of Tampere – Biomimetic and controlled environment for culturing and assessing the functionality of the disease specific iPS-derived cardiomyocytes.

17:25-18:15 – John Wikswo, Vanderbilt University – MicroPhysiological Systems: Organoids, Organs-on-Chips, Analytical Systems, and Control – Keynote   

18:30 – Reception

May 25, 2018
8:30-8:35 – Welcome to Day 2

8:35-9:25 – Róisín M. Owens, Cambridge University – The world is not flat: 3D cell biology integrated with 3D conducting polymer devices – Keynote

9:25-9:45 – Jannick Theobald, Heidelberg University – Liver-Kidney Chip to mimic drug metabolism and toxicity

9:45-10:05 – Bernhard Müller, TU Graz – Respiration and acidification rates of mammal cell cultures in microfluidic devices utilizing integrated optical chemical sensors

10:05-11:30 – Poster Session 2 and Coffee Break (15 posters)

11:30-11:50 – Mathias Busek, Technische Universität Dresden – Enhanced cardiomyocyte maturation in a microfluidic system as a potential platform for pharmacological screening

11:50-12:10 – Peter D. Jones, NMI – Microfluidic microelectrode arrays: high-content readout from compartmentalized cell culture models

12:10-12:30 – O. Tomilova – HepaChip-MWP – towards a microfluidic, perfusable and scalable in vitro model of the liver in multiwellplate format

12:40-13:30 – Lunch

13:30-14:20 – Liudmila Polonchuk, Roche pRED – Advanced Cell Models, Organs on Chips & Microphysiological Systems in Drug Development: An End User Perspective – Keynote

14:20-14:40 – Linda Gijzen, Mimetas BV – 3D NephroScreen: high throughput drug-induced nephrotoxicity screening on a proximal tubule-on-a-chip model

14:40-15:00 – Fabrizio Hürlimann – Predicting hepatic compound clearance using a microphysiological system based on human liver microtissues

15:00-15:15 – Break

15:15-15:35 – Stéphanie Descroix, Institut Curie CNRS – A physiological gut on chip replicating small intestine complexity

15:35-15:55 – Pranjul Shah, University of Luxembourg – HuMiX: An microfluidics-based model of the human gastrointestinal hostmicrobe interface

15:55-16:15 – Michelle Maurer, University Hospital Jena – Development of a human gut-on-chip model to study macrophage dependent inflammatory response

16:15-16:35 – Alexander Mosig, Jena University Hospital – Emulating the Gut-Liver Axis – Organ-on-chip as Translational Tool in Sepsis Research

16:35-16:45 – Closing


Registration opens February 1, 2018

€250 – Full Conference Registration

€50 – Conference Banquet and Cocktail Reception

Thank you to our venue sponsor

Sponsorship and Exhibit Opportunities Available!

Sponsorship and exhibit opportunities at available! Click on the links below for more information.

Conference Organizing Committee

Conference Organizing Committee:

Maria Tenje
Associate Professor
Uppsala University

Peter Loskill – Chair
Assistant Professor
Fraunhofer IGB/ University of Tübingen

Torsten Mayr
Associate Professor
Graz University of Technology

Alexander Mosig
Assistant Professor
Jena University Hospital

Conference Location

EUROoC Conference will be held at the Fraunhofer Institute for Interfacial Engineering and Biotechnology.

Nobelstrasse 12
70569 Stuttgart
Phone +49 711 970-4401

By car
Leave motorway A 81 or A 8 at the “Stuttgarter
Kreuz” junction. Take the A 831 in the direction
of “Stuttgart Zentrum” (City center) and exit at
“Universität”. Turn left at the traffic lights onto
Universitätsstrasse and keep straight on until Universitätsstrasse
becomes Nobelstrasse after a sharp bend
to the right. After a further 400 m, the Fraunhofer-
Institutszentrum will appear on the right.

By train
From Stuttgart’s main station (Hauptbahnhof), take
either the S-Bahn (city rail) S1 (towards Herrenberg),
S2 or S3 (both towards Airport), all departing from
platform 101 on the lower level underneath the train
station. Get off at the “Universität” station and follow
the signs there to the “Wohngebiet Schranne / Endelbang
/ Nobelstrasse” exit. You are now on Universitätsstrasse
where you will find signs directing you to
“Fraunhofer-Gesellschaft” (approx. 650 m).
Alternatively, take bus no. 84 or 92 from the “Universität”
station to the “Nobelstrasse” bus-stop. Plan
approx. 30 minutes from the main station to the IGB
building (this includes walking time).

By plane
From Stuttgart airport, take the S-Bahn (city rail) S2
or S3 in the direction of Stuttgart-Vaihingen / Hauptbahnhof.
Get off at the “Universität” station and
continue as described directly above. A taxi from the
airport will cover the distance of 14 km in approx. 20